一种新型的细丝将有助于抵抗艾滋病毒的传播
Copper3D is a Chilean/US-based company that discovered a new mode of application for proprietary filament with copper nanoparticles. As products developed from such materials are very effective in terms of inactivating HIV, they can prove extremely useful in the construction of 3D-printed breastfeeding filters. Such applications cannot be considered new, since 3D printing is widely used for
Copper3D是一家位于智利/美国的公司，发现了具有铜纳米颗粒的专有灯丝的新应用模式。 由于用这种材料开发的产品在灭活HIV方面非常有效，因此它们在3D打印的母乳喂养过滤器的构造中非常有用。 由于3D打印广泛用于medicinal purposes.医疗目的，因此不能认为此类应用是新的。 Copper is known for its antibacterial properties and is currently being researched for its efficacy in terms of viral inactivation. For example, back in 2009, a group of British scientists from the University of Southampton found out that copper is quite effective against A/H1N1 — a flu virus also known as the “swine flu”. The Chilean scientists, in their turn, state that the properties of composite polymer filament with copper nanoparticles they developed are not only antibacterial, but also optimal for HIV inactivation. 铜以其抗菌特性而闻名，目前正就病毒灭活方面的功效进行研究。 例如，早在2009年，来自南安普敦大学的一群英国科学家发现，铜对A / H1N1流感病毒(又称“猪流感”)非常有效。 智利科学家则指出，他们开发的具有铜纳米颗粒的复合聚合物长丝的特性不仅具有抗菌性，而且对于灭活HIV也是最佳的。
Copper3D was founded by Daniel Martinez, Andres Acuña and Claudio Soto — a group of experts with a great deal of relevant background experience. Daniel is a physical therapist, Andres is an electronic engineer and Claudio is a rehabilitation expert. In order to test the filament capabilities, the team commissioned laboratory research. During the study, samples of the HIV-1 were placed into containers with a 40 cm² surface area made from PLACTIVE and then compared against the control group. The samples were kept inside the containers for different periods of time: 15 seconds, 1 minute, 2 minutes, and 15 minutes respectively.
Copper3D由丹尼尔·马丁内斯(Daniel Martinez)，安德烈斯·阿库尼亚(AndresAcuña)和克劳迪奥·索托(Claudio Soto)创立，他们是一群具有大量相关背景经验的专家。 Daniel是物理治疗师，Andres是电子工程师，Claudio是康复专家。 为了测试灯丝的功能，该团队委托实验室进行研究。 在研究过程中，将HIV-1样品放入由PLACTIVE制造的表面积为40cm²的容器中，然后与对照组进行比较。 将样品在容器中放置不同的时间：分别为15秒，1分钟，2分钟和15分钟。
Daniel Martinez commented on the outcome: “The preliminary results showed a reduction of viral replication of up to 58.6% by simply exposition of the samples to the 3D printed boxes containing copper nanoparticles. Fifteen seconds of exposition were enough to achieve such a reduction. These data allow us to infer that by increasing the contact surface by a factor of 10X, we could obtain much higher inactivation rates, very close to 100% and according to our calculations, most probably in less than 5 seconds.”
丹尼尔·马丁内斯(Daniel Martinez)对结果进行了评论：“初步结果显示，只需将样品暴露于含有铜纳米颗粒的3D打印盒中，病毒复制最多可减少58.6％。 十五秒钟的曝光足以实现这种减少。 这些数据使我们推断出，通过将接触表面增加10倍，我们可以获得更高的灭活率，非常接近100％，根据我们的计算，很可能不到5秒。
Such a solution is expected to help HIV-positive mothers feed their babies without exposing them to the virus. It will certainly be of use in developing countries, where breastfeeding is the main way of HIV transmission. According to the WHO, mothers that don’t take any antiretroviral drugs as a part of their HIV treatment therapy have a 14-20% chance of infecting the baby when feeding. On the contrary, if a mother received enough treatment, the chances of transmission drop to 1-2% over the course of the first twelve months. In order to further diminish the breastfeeding HIV transmission rate, Copper3D is waiting for its patent application for the above-mentioned viral inactivation devices to be approved. The filters are expected to be fully functional and completed over the current year.
预期这种解决方案将帮助艾滋病毒呈阳性的母亲喂养婴儿，而不会使他们接触该病毒。 在母乳喂养是艾滋病毒传播的主要方式的发展中国家中，它肯定会有用。 根据世界卫生组织(WHO)的数据，未将任何抗逆转录病毒药物作为其HIV治疗疗法的一部分的母亲在喂养婴儿时有14-20％的机会感染婴儿。 相反，如果母亲接受了足够的治疗，则在最初的12个月中，传播的机会下降到1-2％。 为了进一步降低母乳喂养的HIV传播率，Copper3D正在等待其上述病毒灭活装置的专利申请获得批准。 这些过滤器有望在今年完成全部功能并完工。
Currently, Copper3D offers several specialized consumables for FDM 3D-printers. The material lineup consists of PLACTIVE (polylactide), NanoClean (PETG) and MDflex (thermoplastic polyurethane). Since January 2019, the official designated distributor of products for the European market is 3DGBIRE, a UK-based company. Another recently appointed distributor is FormFutura, a Dutch-based company that began selling the filament via its official website a month ago.
目前，Copper3D为FDM 3D打印机提供了几种专用耗材。 材料阵容包括PLACTIVE(聚丙交酯)，NanoClean(PETG)和MDflex(热塑性聚氨酯)。 自2019年1月以来，面向欧洲市场的产品的官方指定分销商是英国公司3DGBIRE。 另一个最近任命的分销商是荷兰的FormFutura公司，该公司一个月前开始通过其官方网站出售长丝。